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Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells

作者:H. Zhang, Hangqi Zhang, Ming Li, Xueming Zhou, Li Tang, Guang‐Ying Chen, Yongmin Zhang · 发表于:European Journal of Medicinal Chemistry · 年份:2024 · DOI:10.1016/j.ejmech.2024.116497 · 被引用次数:17 · 研究领域:Autophagy in Disease and Therapy、Click Chemistry and Applications、Ubiquitin and proteasome pathways