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Associations Between Antiretroviral Regimen and Changes in Blood Pressure: Results From the D2EFT Study

作者:Phyo Pyae Nyein, Kathy Petoumenos, Margaret Borok, Nnakelu Eriobu, Nagalingeswaran Kumarasamy, Anchalee Avihingsanon, Iskandar Azwa, Sounkalo Dao, Mohamed Cissé, Nila J. Dharan, Josh Hanson, Gail Matthews · 发表于:Clinical Infectious Diseases · 年份:2024 · DOI:10.1093/cid/ciae256 · 被引用次数:10 · 研究领域:HIV-related health complications and treatments、Blood Pressure and Hypertension Studies、Neurological Complications and Syndromes

In this randomized controlled study, individuals taking dolutegravir+darunavir/ritonavir had greater increases in systolic and diastolic blood pressure than those taking 2 nucleoside reverse-transcriptase inhibitors+darunavir/ritonavir at week-48. The difference remained significant after controlling for confounding factors, including weight gain.