The investigation on stress mechanisms of Sepia esculenta larvae in the context of global warming and ocean acidification

作者：Yongjie Wang, Xiumei Liu, Weijun Wang, Guohua Sun, Feng Yanwei, Xiaohui Xu, Bin Li, Qihao Luo, Yan Li, Jianmin Yang, Cuiju Cui, Zan Li · 发表于：Aquaculture Reports · 年份：2024 · DOI：10.1016/j.aqrep.2024.102120 · 被引用次数：26 · 研究领域：Cephalopods and Marine Biology、Insect and Arachnid Ecology and Behavior、Neurobiology and Insect Physiology Research

Sepia esculenta is a tasty and nutritious cephalopod. But the trend toward global warming is accelerating with massive emissions of greenhouse gases. An increase in seawater temperature and a decrease in pH are a great challenge for artificial breeding and culture of S. esculenta. In this study, we investigated the contingency mechanism of S. esculenta larvae under both high temperature and low pH conditions by transcriptome analysis. A total of 1235 DEGs were identified. functional enrichment analysis results suggest that high temperature and low pH conditions led to malignant proliferation in exceptional cells of S. esculenta larvae. A comprehensive analysis of the KEGG signaling pathway and protein-protein interaction network (PPI) identified sixteen key genes under both high temperature and low pH conditions. The three genes with the highest quantities of interactions or involved in more KEGG signaling pathways were identified as hub genes affecting normal physiological processes in S. esculenta. In this study, the effects of global warming and ocean acidification on the metabolism and immunity of S. esculenta larvae were preliminarily investigated to provide necessary help for S. esculenta captive breeding in the face of global climate change.