5-Fluorouracil resistant CRC cells derived exosomes promote cancer-associated fibroblasts secreting more CXCL12

作者：Tongxin Zhang, Zilong He, Xiaowei Qi, Yu Zhang, Yankui Liu, Linfang Jin, Teng Wang · 发表于：Journal of Cancer · 年份：2024 · DOI：10.7150/jca.95248 · 被引用次数：6 · 研究领域：Galectins and Cancer Biology、Extracellular vesicles in disease、Endoplasmic Reticulum Stress and Disease

Chemoresistant CRC cells can induce CAFs activation and promote CXCL12 secretion through exosomal TRPC5.