CoH-catalyzed asymmetric remote hydroalkylation of heterocyclic alkenes: a rapid approach to chiral five-membered S- and O-heterocycles

作者：Lingzi Zhao, Feipeng Liu, Yan Zhuang, Mengyang Shen, Jing Xue, Xuchao Wang, Yuting Zhang, Zi‐Qiang Rong · 发表于：Chemical Science · 年份：2024 · DOI：10.1039/d4sc01149j · 被引用次数：10 · 研究领域：Catalytic C–H Functionalization Methods、Synthesis and Catalytic Reactions、Asymmetric Hydrogenation and Catalysis

A highly efficient method achieves precise construction of alkyl chiral centers at remote C3-positions in five-membered S/O-heterocycles via cobalt-catalyzed asymmetric remote hydroalkylation of heterocyclic alkenes.