Novel Providencia xianensis sp. nov.: A multidrug-resistant species identified in clinical infections

作者：Xu Dong, Yanghui Xiang, Peihong Yang, Shanmei Wang, Wenjuan Yan, Youhua Yuan, Shan Zhou, Ke Zhou, Jiayun Liu, Ying Zhang · 发表于：European Journal of Clinical Microbiology & Infectious Diseases · 年份：2024 · DOI：10.1007/s10096-024-04821-y · 被引用次数：7 · 研究领域：Plant Pathogens and Fungal Diseases、Infections and bacterial resistance、Infectious Diseases and Mycology

Providencia genus is known to harbor certain opportunistic pathogens capable of causing human infections. Here, we report two strains of multidrug-resistant bacteria initially identified as Providencia rettgeri by mass spectrometry, but genome analysis revealed their ANI (79.84-84.20%) and dDDH (21.1-25.6%) values to fall below the accepted species threshold for known Providencia species. We therefore propose that these isolates be recognized as a novel species, Providencia xianensis sp. nov. Alarmingly, both strains, isolated from locations far apart, exhibited resistance to last-resort antibiotics, indicating their possible wide distribution, underscoring the urgency for immediate attention and enhanced surveillance for this emerging multidrug-resistant pathogen.