Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis

作者：Zhi Zong, Feng Xie, Shuai Wang, Xiaojin Wu, Zhenyu Zhang, Bing Yang, Fangfang Zhou · 发表于：Cell · 年份：2024 · DOI：10.1016/j.cell.2024.04.002 · 被引用次数：572 · 研究领域：RNA modifications and cancer、Cancer-related Molecular Pathways、Cancer, Hypoxia, and Metabolism