Modulation of immune responses in the central nervous system by Zika virus, West Nile virus, and dengue virus

作者：Shuhui Wu, Ting Zhang, Weidong Qiang, Yang Yang · 发表于：Reviews in Medical Virology · 年份：2024 · DOI：10.1002/rmv.2535 · 被引用次数：7 · 研究领域：Mosquito-borne diseases and control、Viral Infections and Vectors、Vector-borne infectious diseases

Arthropod-borne viruses (arboviruses) pose significant threats to global public health by causing a spectrum of diseases ranging from mild febrile illnesses to severe neurological complications. Understanding the intricate interplay between arboviruses and the immune system within the central nervous system is crucial for developing effective strategies to combat these infections and mitigate their neurological sequelae. This review comprehensively explores the mechanisms by which arboviruses such as Zika virus, West Nile virus, and Dengue virus manipulate immune responses within the CNS, leading to diverse clinical manifestations.