Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles

作者：Saori Sakaue, Kathryn Weinand, Shakson Isaac, Kushal K. Dey, Karthik A. Jagadeesh, Masahiro Kanai, Gerald F. Watts, Zhu Zhu, Accelerating Medicines Partnership® RA/SLE Program and Network, Jennifer S. Albrecht, Jennifer H. Anolik, William A. Apruzzese, Nirmal K. Banda, Jennifer L. Barnas, Joan M. Bathon, Ami Ben‐Artzi, Brendan F. Boyce, David L. Boyle, S. Louis Bridges, Vivian P. Bykerk, Debbie Campbell, Hayley L. Carr, Arnold Ceponis, Adam T. Chicoine, Andrew C. Cordle, Michelle L. Curtis, Kevin D. Deane, Edward F. DiCarlo, Patrick J. Dunn, Andrew D. Filer, Gary S. Firestein, Lindsy J. Forbess, Laura B. Geraldino-Pardilla, Susan M. Goodman, Ellen M. Gravallese, Peter K. Gregersen, Joel M. Guthridge, María Gutiérrez‐Arcelus, Siddarth Gurajala, V. Michael Holers, Diane Michelle Horowitz, Laura B. Hughes, Kazuyoshi Ishigaki, Lionel B. Ivashkiv, Judith A. James, Anna Helena Jonsson, Joyce B. Kang, Gregory Keras, Ilya Korsunsky, Amit Lakhanpal, James Arthur Lederer, Zhihan J. Li, Yuhong Li, Katherine P. Liao, Arthur M. Mandelin, Ian Mantel, Mark Maybury, Joseph Mears, Nida Meednu, Nghia Millard, Larry W. Moreland, Aparna Nathan, Alessandra Nerviani, Dana E. Orange, Harris Perlman, Costantino Pitzalis, Javier Rangel‐Moreno, Deepak A. Rao, Karim Raza, Yakir Reshef, Christopher T. Ritchlin, Felice Rivellese, William H. Robinson, Laurie Rumker, Ilfita Sahbudin, Jennifer A. Seifert, Kamil Slowikowski, Melanie H. Smith, Darren Tabechian, Dagmar Scheel‐Toellner, Paul J. Utz, Dana Weisenfeld, Michael H. Weisman, Qian Xiao, Fan Zhang, Michael B. Brenner, Andrew McDavid, Laura T. Donlin, Kevin S. Wei, Alkes L. Price, Soumya Raychaudhuri · 发表于：Nature Genetics · 年份：2024 · DOI：10.1038/s41588-024-01682-1 · 被引用次数：55 · 研究领域：Single-cell and spatial transcriptomics、Cancer Genomics and Diagnostics、Gene expression and cancer classification