Electrochemical E -Selective Semireductive Dicarboxylation of Aryl Alkynes with CO 2

作者：Lan Zhao, Wen‐Jun Xie, Zheng-Zheng Meng, Hongru Li, Liang‐Nian He · 发表于：Organic Letters · 年份：2024 · DOI：10.1021/acs.orglett.4c00860 · 被引用次数：29 · 研究领域：CO2 Reduction Techniques and Catalysts、Carbon dioxide utilization in catalysis、Radical Photochemical Reactions

Herein, we report an electrochemical protocol for the dicarboxylation of aryl alkynes using CO 2 . With a graphite rod as the cathode and Al as the sacrificial anode, a series of valuable butenedioic acids are obtained in moderate to excellent yields with an E / Z ratio up to 50:1. This method features high E -selectivity, high step and atom economy, easy scalability, and a nice substrate scope, which renders it appealing for promising applications in organic synthesis and materials chemistry.