Association between Body Mass Index and Medication-Overuse Headache among Individuals with Migraine: A Cross-Sectional Study

作者：Huanxian Liu, Hongru Zhao, Kaiming Liu, Zhihua Jia, Ming Dong, Yingying Cheng, Yudan Lv, Kang Qu, Wei Gui, Jianjun Chen, Dan Zhang, Zhiliang Fan, Xiaosu Yang, Dongmei Hu, Hongyan Xie, Mingxin Li, Bing Wen, Sufen Chen, Xu Peng, Qingqing Rong, Qiu He, Zhanxiu Ren, Fanhong Yan, Heling Zhao, Min Chen, Tingmin Yu, Hongli Qu, Xingkai An, Huailian Guo, Xinhua Zhang, Xiaoping Pan, Xiaojuan Wang, Shi Qiu, Lvming Zhang, Hongling Zhao, Xin Pan, Qing Wan, Lanyun Yan, Jing Liu, Zhe Yu, Mingjie Zhang, Ye Ran, Xun Han, Zhao Dong, Shengyuan Yu · 发表于：Obesity Facts · 年份：2024 · DOI：10.1159/000538528 · 被引用次数：6 · 研究领域：Migraine and Headache Studies、Fibromyalgia and Chronic Fatigue Syndrome Research、Musculoskeletal pain and rehabilitation

INTRODUCTION: Medication-overuse headache (MOH) is a secondary chronic headache disorder that occurs in individuals with a pre-existing primary headache disorder, particularly migraine disorder. Obesity is often combined with chronic daily headaches and is considered a risk factor for the transformation of episodic headaches into chronic headaches. However, the association between obesity and MOH among individuals with migraine has rarely been studied. The present study explored the association between body mass index (BMI) and MOH in people living with migraine. METHODS: This cross-sectional study is a secondary analysis of data from the Survey of Fibromyalgia Comorbidity with Headache study. Migraine and MOH were diagnosed using the criteria of the International Classification of Headache Disorders, 3rd Edition. BMI (kg/m2) is calculated by dividing the weight (kg) by the square of the height (m). Multivariable logistic regression analysis was used to evaluate the association between BMI and MOH. RESULTS: A total of 2,251 individuals with migraine were included, of whom 8.7% (195/2,251) had a concomitant MOH. Multivariable logistic regression analysis, adjusted for age, sex, education level, headache duration, pain intensity, headache family history, chronic migraine, depression, anxiety, insomnia, and fibromyalgia, demonstrated there was an association between BMI (odds ratio [OR], 1.05; 95% confidence interval [CI], 1.01-1.11; p = 0.031) and MOH. The results remained when...