Poor Rhinitis and Asthma Control Is Associated With Decreased Health-Related Quality of Life and Utilities: A MASK-air Study

作者：Rafael José Vieira, Lucas Leemann, Andrew H. Briggs, Ana Margarida Pereira, Marine Savouré, Piotr Kuna, Mário Morais‐Almeida, M. Bewick, Luís Filipe Azevedo, Renaud E. Louis, Ludger Klimek, Farah Bahbah, Boleslaw Krzysztof Samolinski, Josep Maria Anto, Torsten Zuberbier, João Fonseca, Jean Bousquet, Bernardo Sousa‐Pinto, Wienczyslawa Czarlewski, Anna Bedbrook, Tari Haahtela, Giorgio Walter Canonica, Elisio M. Costa, Maciej Kupczyk, Violeta Kvedarienė, Marek Kulus, Désirée E. Larenas‐Linnemann, Oliver Pfaar, Nikolaos G. Papadopoulos, Nhan Pham‐Thi, Frederico Soares Regateiro, Nicolás Roche, Joaquin Sastre, Nicola Scichilone, Luís Taborda‐Barata, Arūnas Valiulis, Arzu Yorgancıoğlu, Maria Teresa Ventura, Rute Almeida, Rita Amaral, Ignacio Javier Ansotegui, Karl‐Christian Bergmann, Sinthia Z. Bosnic-Anticevich, Fulvio Braido, Luisa Brussino, Victória Cardona, Lorenzo Cecchi, Claudia Chaves Loureiro, Cemal Cingi, Álvaro Augusto Cruz, Wytske Johanna Fokkens, Govert de Vries, Bilun Gemicioğlu, Antonio F.M. Giuliana, Tomohisa Linuma, Juan Carlos Ivancevich, Cristina Isabel Oliveira Jácome, Ігор Петрович Кайдашев, Helga Kraxner, Daniel Laune, Gilles Louis, Olga M. Lourenço, Mika Juhani Mäkelä, Michael P. Makris, Ralph Mösges, Marcus Maurer, Joaquim Mullol, Rachel Nadif, Marek Niedoszytko, Robyn E. O’Hehir, Yoshitaka Okamoto, Markus W. Ollert, Heidi Olze, Vincenzo Patella, Benoît Pétré, Francesca Puggioni, Jan Romantowski, Philip W. Rouadi, Sietze Reitsma, Daniela Rivero‐Yeverino, Mónica Rodríguez-González, Ana Sá‐Sousa, Faradiba Sarquis Serpa, Mohamed H. Shamji, Aziz Sheikh, Charlotte Suppli Ulrik, Mikhail A. Sofiev, Milan Sova, Annette Sperl, Ana Maria Todo‐Bom, Peter Valentin Tomazic, Sanna Katriina Toppila-Salmi, Ioanna Tsiligianni, Erkka Juhani Valovirta, Michiel Van Eerd, Mihaela Zidarn, Hubert Blain, Louis‐Philippe Boulet, Guy Brusselle, Roland Buhl, D. Charpin, Thomas B. Casale, Tomás Chivato, Jaime Correia-de-Sousa, Christopher John Corrigan, Frederic de BLAY, Stefano Del Giacco, Philippe Devillier, Mark S. Dykewicz, Alessandro Giovanni Fiocchi, Mattia Giovannini, Ewa Jassem, Marek Jutel, Thomas Oskar Philipp Keil, Stefania La Grutta, Brian Jonathon Lipworth, Alberto A. Papi, Jean‐Louis Pépin, Santiago Quirce, Carlos Robalo Cordeiro, Marı́a José Torres, Omar S. Usmani · 发表于：The Journal of Allergy and Clinical Immunology In Practice · 年份：2024 · DOI：10.1016/j.jaip.2024.03.036 · 被引用次数：23 · 研究领域：Allergic Rhinitis and Sensitization、Asthma and respiratory diseases、Dermatology and Skin Diseases

BACKGROUND: Allergic rhinitis (AR) and asthma may affect health-related quality of life. However, national estimates on the quality of life of patients with AR or asthma are lacking. OBJECTIVE: To provide estimates for utility scores and EuroQoL five-dimension (EQ-5D) visual analog scale (VAS) for patients with AR or asthma. METHODS: We conducted a cross-sectional study using direct patient data from the MASK-air app on European MASK-air users with self-reported AR or asthma. We used a multi-attribute instrument (EQ-5D) to measure quality of life (as utility scores and EQ-5D VAS values). Mean scores were calculated per country and disease control level using multilevel regression models with poststratification, accounting for age and sex biases. RESULTS: We assessed data from 7905 MASK-air users reporting a total of up to 82,737 days. For AR, utilities ranged from 0.86 to 0.99 for good control versus 0.72 to 0.85 for poor control; EQ-5D VAS levels ranged from 78.9 to 87.9 for good control versus 55.3 to 64.2 for poor control. For asthma, utilities ranged from 0.84 to 0.97 for good control versus 0.73 to 0.87 for poor control; EQ-5D VAS levels ranged from 68.4 to 81.5 for good control versus 51.4 to 64.2 for poor control. Poor disease control was associated with a mean loss of 0.14 utilities for both AR and asthma. For the same control levels, AR and asthma were associated with similar utilities and EQ-5D VAS levels. However, lower values were observed for asthma plus AR compa...