Acute Effects of Exposure to Fine Particulate Matter and Its Constituents on Sex Hormone Among Postmenopausal Women — Beijing, Tianjin, and Hebei PLADs, China, 2018–2019

作者：Yanlin Tian, Jiaonan Wang, Jianlong Fang, Chen Chen, Feng Zhao, Yi Zhang, Peng Du, Yawei Li, Wanying Shi, Yuanyuan Liu, Enmin Ding, Song Tang, Xu Yue, Xiaoming Shi · 发表于：China CDC Weekly · 年份：2024 · DOI：10.46234/ccdcw2024.049 · 被引用次数：7 · 研究领域：Air Quality and Health Impacts、Climate Change and Health Impacts、Medical and Agricultural Research Studies

What is already known on this topic? Exposure to fine particulate matter (PM 2.5 ) was linked to endocrine hormone disruption in the reproductive system. Nonetheless, it was unclear which specific components of PM 2.5 were primarily responsible for these associations. What is added by this report? The study presented the initial epidemiological evidence that brief exposure to PM 2.5 can elevate estradiol levels in postmenopausal women. Various particle components had unique effects, with water-soluble ions and specific inorganic elements like Ag, As, Cd, Hg, Ni, Sb, Se, Sn, and Tl potentially playing significant roles in increasing estradiol levels. What are the implications for public health practice? The study established that the prevalence of air pollution, along with its specific components, has been recognized as a novel risk factor affecting the balance of sex hormones.