Research progress on the osteogenic properties of tantalum in the field of medical implant materials

作者：Xi Wang, Wentao Liu, Chundong Jiang, Peng Pan, Tiantian Chen, Xinwen Zhang, Xu Yan · 发表于：Journal of Materials Research and Technology · 年份：2024 · DOI：10.1016/j.jmrt.2024.03.200 · 被引用次数：11 · 研究领域：Bone Tissue Engineering Materials、Orthopaedic implants and arthroplasty、Titanium Alloys Microstructure and Properties

Ideal medical implant materials should have the qualities of osteoinduction, osteoconduction, nontoxicity, non-sensitivity and non-carcinogenicity to the body. Although its high melting point and high elastic modulus pose difficulties for processing technology, tantalum has become a popular research topic in the field of medical implant materials because of its excellent biocompatibility and bone inductivity. In this paper, the performance of the bone-inducing properties of tantalum in different applications, including its combination with other elements, its use as a coating, its porous structure and its surface modification ability, are summarized. The mechanism of promoting bone formation and the clinical application of tantalum are reviewed.