Sodium Intake and Cause-Specific Mortality Among Predominantly Low-Income Black and White US Residents

作者：Hyung‐Suk Yoon, Qiuyin Cai, Jae Jeong Yang, Loren Lipworth, Hui Cai, Danxia Yu, Mark Steinwandel, Deepak K. Gupta, William J. Blot, Wei Zheng, Xiao‐Ou Shu · 发表于：JAMA Network Open · 年份：2024 · DOI：10.1001/jamanetworkopen.2024.3802 · 被引用次数：11 · 研究领域：Sodium Intake and Health、Nutritional Studies and Diet、Electrolyte and hormonal disorders

IMPORTANCE: Epidemiologic evidence regarding the outcomes of dietary sodium intake on mortality remains limited for low-income individuals, particularly Black people. OBJECTIVE: To investigate the associations of excessive dietary sodium with all-cause and cause-specific mortality among predominantly low-income Black and White Americans. DESIGN, SETTING, AND PARTICIPANTS: This cohort study included participants aged 40 to 79 years from the Southern Community Cohort Study who were recruited at Community Health Centers in 12 southeastern states from 2002 to 2009. Analyses were conducted between March 2022 and June 2023. EXPOSURES: Dietary sodium intake was assessed using a validated food frequency questionnaire at baseline. MAIN OUTCOMES AND MEASURES: Multivariable-adjusted Cox regression was used to estimate hazard ratios (HRs) and 95% CIs for mortality outcomes (all-cause, cardiovascular disease [CVD], coronary heart disease [CHD], stroke, heart failure, cancer, and other) associated with sodium intake. Nonlinear associations and population-attributable risk (PAR) of the mortality burden associated with excess sodium were further assessed. RESULTS: Among the 64 329 participants, 46 185 (71.8%) were Black, 18 144 (28.2%) were White, and 39 155 (60.9%) were female. The mean (SD) age at study enrollment was 51.3 (8.6) years for Black participants and 53.3 (9.3) years for White counterparts. Mean (SD) dietary sodium intake was 4512 (2632) mg/d in Black individuals and 4041 (2227)...