Radical cascade silylation/cyclization of 1,7-dienes to access silyl-substituted benzo[ b ]azepin-2-ones

作者：Zhen Zhang, Lichao Lu, Guiling Li, Xiaoyu Sheng, Yijia Zhang, Lin Yang, Jiaqi Zhao, Lei Xie, Jiazhu Li, Kai Sun · 发表于：Chemical Communications · 年份：2024 · DOI：10.1039/d4cc00499j · 被引用次数：16 · 研究领域：Catalytic C–H Functionalization Methods、Asymmetric Synthesis and Catalysis、Chemical synthesis and alkaloids

]azepin-2-ones. Several control experiments suggest that the reaction undergoes a free radical process. The gram-scale synthesis and late-stage transformations further demonstrate the scalability and applicability of the reaction in organic synthesis.