The Parkinson’s disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons

作者：Jace Jones-Tabah, Kathy He, Konstantin Senkevich, Nathan Karpilovsky, Ghislaine Deyab, Yuting Cousineau, Daria Nikanorova, Taylor Goldsmith, Esther del-Cid Pellitero, Carol X.‐Q. Chen, Wen Luo, Zhipeng You, Narges Abdian, Isabella Pietrantonio, Thomas Goiran, Jamil Ahmad, Jennifer A. Ruskey, Farnaz Asayesh, Dan Spiegelman, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupré, Irina Miliukhina, Alla Timofeeva, Anton Emelyanov, Sofya Pchelina, Lior Greenbaum, Sharon Hassin‐Baer, Roy N. Alcalay, Austen J. Milnerwood, Thomas M. Durcan, Ziv Gan‐Or, Edward A. Fon · 发表于：Research Square · 年份：2024 · DOI：10.21203/rs.3.rs-3979098/v1 · 被引用次数：4 · 研究领域：Parkinson's Disease Mechanisms and Treatments、Lysosomal Storage Disorders Research、Nuclear Receptors and Signaling