Postpartum Haemorrhage Risk Prediction Model Developed by Machine Learning Algorithms: A Single-Centre Retrospective Analysis of Clinical Data

作者：Wenhuan Wang, Chanchan Liao, Hong Ping Zhang, Yanjun Hu · 发表于：Clinical and Experimental Obstetrics & Gynecology · 年份：2024 · DOI：10.31083/j.ceog5103060 · 被引用次数：10 · 研究领域：Trauma and Emergency Care Studies

Background: Postpartum haemorrhage (PPH) is a serious complication and a cause of maternal mortality after delivery. This study used machine learning algorithms and new feature selection methods to build an efficient PPH risk prediction model and provided new ideas and reference methods for PPH risk management. Methods: The clinical data of women who gave birth at Wenzhou People’s Hospital from 1 January 2021, to 30 March 2022, were retrospectively analysed, and the women were divided into a high haemorrhage group (337 patients) and a low haemorrhage group (431 patients) based on the amount of blood loss. Machine learning algorithms were used to identify the features associated with postpartum haemorrhage from multiple clinical variables using feature selection methods, such as recursive feature elimination (RFE), recursive feature elimination with cross-validation (RFECV), and SelectKBest, and to establish prediction models. Results: For all women, the features associated with postpartum haemorrhage were ‘age’, ‘newborn weight’, ‘gestational week’, ‘perineal laceration’, and ‘caesarean section’. The prediction model established by the random forest classifier performed best, with an F1 score of 0.73 and an area under the curve (AUC) of 0.84. For women who underwent caesarean section or had a vaginal delivery, the features associated with postpartum haemorrhage risk were different. The risk factors for postpartum haemorrhage in women who underwent caesarean section were ‘age’...