Opposing Effects of Nutritional Supply on Bone Health at Different Ages: Based on the National Health and Nutrition Examination Survey Database

作者：Jieqiong Wei, Yaxi Zhang, Yuehan Yuan, Min Li, Bingfang Zhai, Jihua Chen · 发表于：Nutrients · 年份：2024 · DOI：10.3390/nu16060758 · 被引用次数：5 · 研究领域：Bone health and osteoporosis research、Folate and B Vitamins Research、Nutrition and Health in Aging

(1) Background: Nutrients play an essential role in bone health, whether in achieving peak bone mineral density (BMD) or maintaining bone health. This study explores the relationship between nutrient supply and femoral bone health at different ages. (2) Methods: A total of 5603 participants meeting the inclusion and exclusion criteria were included in this study using the National Health and Nutrition Examination Survey (NHANES) database from 2005 to 2010, 2013 to 2014, and 2017 to 2018. Femoral bone mineral density and bone status were dependent variables, and dietary nutrient intake and nutrient intake status were independent variables. The relationship between dietary nutrient intake and bone mineral density was explored, and the importance of nutrients affecting bone status was analyzed through a neural network model. At the same time, we investigated the relationship between nutrient intake and bone status. (3) Results: The peak of age and femoral bone mineral density appeared at 20 years old in our study. After grouping by age, logistic regression analysis showed that before 20 years old, without adjusting other variables, high-fat diet was more likely to have normal bone mass than appropriate fat diet (OR: 4.173, 95%CI: 1.007–17.289). After adjusting for all demographic factors, niacin intake (OR: 1.062, 95%CI: 1.019–1.108) was beneficial for normal bone mass, while vitamin B6 intake (OR: 0.627, 95%CI: 0.408–0.965) was not. After 20 years old, after adjusting for carbo...