Effect of Intermittent Thoracic Paravertebral Block on Postoperative Nausea and Vomiting Following Thoracoscopic Radical Resection of the Lung Cancer: A Prospective Randomized Trial

作者：Ting Ma, Yulong Yu, Haihua Cao, Huiqin Wang, Mingcang Wang · 发表于：Journal of Pain Research · 年份：2024 · DOI：10.2147/jpr.s453615 · 被引用次数：5 · 研究领域：Nausea and vomiting management、Anesthesia and Pain Management、Cancer, Stress, Anesthesia, and Immune Response

Purpose: To explore the benefits of ultrasound-guided intermittent thoracic paravertebral block (TPVB) combined with intravenous analgesia (PCIA) in alleviating postoperative nausea and vomiting (PONV) during video-assisted thoracic surgery (VATS). Patients and Methods: 120 patients with lung carcinoma undergoing VATS were included and divided into three groups: group S (single TPVB+PCIA), group I (intermittent TPVB+PCIA), and group P (PCIA). The patients’ NRS scores, postoperative hydromorphone hydrochloride consumption, and intramuscular injection of bucinnazine hydrochloride were recorded. The incidence of PONV and complications were documented. Results: Compared with the group P, both group I and group S had significantly lower static NRS scores from 1– 48 hours after the operation ( P < 0.05), and the dynamic NRS score of group I at the 1– 48 hours after the operation were significantly decreased ( P < 0.05). Compared with the group P, the proportion of patients with PONV in group I was significantly lower ( P < 0.05), while there was no significant difference in group S. Moreover, the hospitalization period of patients in group I was significantly reduced compared with the other two groups ( P < 0.01), and the patient satisfaction was significantly increased compared with the group P ( P < 0.05). Conclusion: Intermittent TPVB combined with PCIA can reduce the postoperative pain and the occurrence of PONV. Keywords: thoracic paravertebral block, patient-controlled intrav...