Role of microvascular invasion in early recurrence of hepatocellular carcinoma after liver resection: A literature review

作者：Zhihong Zhang, Chuang Jiang, Zeyuan Qiang, Yifan Zhou, Jun Feng Ji, Yong Zeng, Jiwei Huang · 发表于：Asian Journal of Surgery · 年份：2024 · DOI：10.1016/j.asjsur.2024.02.115 · 被引用次数：47 · 研究领域：Hepatocellular Carcinoma Treatment and Prognosis、Cancer, Lipids, and Metabolism、Cholangiocarcinoma and Gallbladder Cancer Studies

Hepatectomy is widely considered a potential treatment for hepatocellular carcinoma (HCC). Unfortunately, one-third of HCC patients have tumor recurrence within 2 years after surgery (early recurrence), accounting for more than 60% of all recurrence patients. Early recurrence is associated with a worse prognosis. Previous studies have shown that microvascular invasion (MVI) is one of the key factors for early recurrence and poor prognosis in patients with HCC after surgery. This paper reviews the latest literature and summarizes the predictors of MVI, the correlation between MVI and early recurrence, the identification of suspicious nodules or subclinical lesions, and the treatment strategies for MVI-positive HCC. The aim is to explore the management of patients with MVI-positive HCC.