Clonal Distribution and Its Association With the Carbapenem Resistance Mechanisms of Carbapenem-Non-Susceptible Pseudomonas aeruginosa Isolates From Korean Hospitals

作者：Nayeong Kim, Seo Yeon Ko, Seong Yong Park, Seong Yeob Kim, D. Lee, Ki Tae Kwon, Yu Kyung Kim, Je Chul Lee · 发表于：Annals of Laboratory Medicine · 年份：2024 · DOI：10.3343/alm.2023.0369 · 被引用次数：7 · 研究领域：Antibiotic Resistance in Bacteria、Antibiotics Pharmacokinetics and Efficacy、Antibiotic Use and Resistance

Background: isolates from three Korean hospitals. Methods: isolates collected between 2011 and 2019 were analyzed for sequence types (STs), antimicrobial susceptibility, and carbapenem resistance mechanisms, including carbapenemase production, the presence of resistance genes, OprD mutations, and the hyperproduction of AmpC β-lactamase. Results: were identified in all isolates tested, regardless of the presence of MBL genes. Hyperproduction of AmpC was detected in MBL gene-negative isolates. Conclusions: clones.