Discovery of LHF418 as a new potent SOS1 PROTAC degrader

作者：Huifan Li, Minxue Chai, Yihan Chen, Fengtao Zhou, Xiaomei Ren, Jian Xu, Jian Wang, Zhen Wang, Weixue Huang · 发表于：Bioorganic & Medicinal Chemistry · 年份：2024 · DOI：10.1016/j.bmc.2024.117661 · 被引用次数：7 · 研究领域：Protein Degradation and Inhibitors、Ubiquitin and proteasome pathways、Multiple Myeloma Research and Treatments