Endoscopic resection for calcifying fibrous tumors of the gastrointestinal tract

作者：Zi-Han Geng, Yan Zhu, Pei‐Yao Fu, Yi‐Fan Qu, Shi-Yao Chen, Yunshi Zhong, Yiqun Zhang, Weifeng Chen, Wen‐Zheng Qin, Jianwei Hu, Ming‐Yan Cai, Li-Qing Yao, Quan‐Lin Li, Ping‐Hong Zhou · 发表于：World Journal of Clinical Oncology · 年份：2024 · DOI：10.5306/wjco.v15.i2.282 · 被引用次数：4 · 研究领域：IgG4-Related and Inflammatory Diseases、Soft tissue tumor case studies、Medical Imaging and Pathology Studies

BACKGROUND Calcifying fibrous tumors (CFTs) are rare mesenchymal lesions that can occur in various sites throughout the body, including the tubular gastrointestinal (GI) tract. AIM To analyze the clinical findings of 36 patients with GI tract CFTs to provide guidance for diagnosis and treatment. METHODS This retrospective study included 36 patients diagnosed with CFTs of the GI tract. We collected demographic and clinical information and conducted regular follow-ups to assess for local recurrence. RESULTS The stomach was the most commonly involved site, accounting for 72.2% of the 36 CFTs. Endoscopic mucosal resection (n = 1, 2.8%), endoscopic submucosal dissection (n = 14, 38.9%), endoscopic full-thickness resection (n = 16, 44.4%), and submucosal tunneling endoscopic resection (n = 5, 13.9%) were used to resect calcifying fibrous tumors. Overall, 34 (94.4%) CFTs underwent complete endoscopic resections with a mean procedure time of 39.8 ± 29.8 min. The average maximum diameter of the tumors was 10.6 ± 4.3 cm. No complications, such as bleeding or perforation, occurred during an average hospital stay of 2.9 ± 1.2 d. In addition, two patients developed new growth of CFTs near the primary tumor sites, and none of the patients developed distant metastases during the follow-up period. CONCLUSION GI tract CFTs are rare and typically benign tumors that can be effectively managed with endoscopic procedures.