Recent Advances in Electrospinning Techniques for Precise Medicine

作者：Wei Li, Yue Yin, Huaijuan Zhou, Yingwei Fan, Yingting Yang, Qiqi Gao, Pei Li, Ge Gao, Jinhua Li · 发表于：Cyborg and Bionic Systems · 年份：2024 · DOI：10.34133/cbsystems.0101 · 被引用次数：40 · 研究领域：Electrospun Nanofibers in Biomedical Applications、Advanced Sensor and Energy Harvesting Materials、Tissue Engineering and Regenerative Medicine

In the realm of precise medicine, the advancement of manufacturing technologies is vital for enhancing the capabilities of medical devices such as nano/microrobots, wearable/implantable biosensors, and organ-on-chip systems, which serve to accurately acquire and analyze patients' physiopathological information and to perform patient-specific therapy. Electrospinning holds great promise in engineering materials and components for advanced medical devices, due to the demonstrated ability to advance the development of nanomaterial science. Nevertheless, challenges such as limited composition variety, uncontrollable fiber orientation, difficulties in incorporating fragile molecules and cells, and low production effectiveness hindered its further application. To overcome these challenges, advanced electrospinning techniques have been explored to manufacture functional composites, orchestrated structures, living constructs, and scale-up fabrication. This review delves into the recent advances of electrospinning techniques and underscores their potential in revolutionizing the field of precise medicine, upon introducing the fundamental information of conventional electrospinning techniques, as well as discussing the current challenges and future perspectives.