Biological Activities of Secondary Metabolites from the Edible-Medicinal Macrofungi

作者：Xiaoqi Sun, Ying Shi, Dongxiao Shi, Yu Tu, Ling Liu · 发表于：Journal of Fungi · 年份：2024 · DOI：10.3390/jof10020144 · 被引用次数：22 · 研究领域：Fungal Biology and Applications、Phytochemistry and Bioactivity Studies、Microbial Natural Products and Biosynthesis

Macrofungi are well-known as edible-medicinal mushrooms, which belong mostly to Basidiomycota, with a few from Ascomycota. In recent years, macrofungi have been recognized as a rich resource of structurally unique secondary metabolites, demonstrating a wide range of bioactivities, including anti-tumor, antioxidant, anti-inflammatory, antimicrobial, antimalarial, neuro-protective, hypoglycemic, and hypolipidemic activities. This review highlights over 270 natural products produced by 17 families of macrofungi covering 2017 to 2023, including their structures, bioactivities, and related molecular mechanisms.