The effect of music on pain management in preterm infants during daily painful procedures: a systematic review and meta-analysis

作者：Yiran Ou, Ling Chen, Xinyue Zhu, Tianci Zhang, Ye Zhou, Lu Zou, Yun Gao, Zhenghao Wang, Xiaofeng Zheng · 发表于：Frontiers in Pediatrics · 年份：2024 · DOI：10.3389/fped.2024.1351401 · 被引用次数：15 · 研究领域：Pediatric Pain Management Techniques、Infant Development and Preterm Care、Music Therapy and Health

Background The present systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to investigate the effects of music on pain management in preterm neonates during painful procedures. Methods The PubMed, Embase, Web of Science, EBSCO and Cochrane Library databases were searched to identify relevant articles published from their inception to September 2023. The study search strategy and all other processes were implemented in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Results Four RCTs that satisfied the inclusion criteria were included in this meta-analysis. The music group had significantly lower Premature Infant Pain Profile (PIPP) scores during (RR = −1.21; 95% CI = −2.02–−0.40, p = 0.0032) and after painful procedures (RR = −0.65; 95% CI = −1.06–−0.23, p = 0.002). The music group showed fewer changes in PIPP scores after invasive operations than did the control group (RR = −2.06; 95% CI −3.16–−0.96; p = 0.0002). Moreover, our results showed that music improved oxygen saturation during (RR = 3.04, 95% CI = 1.64–4.44, p < 0.0001) and after painful procedures (RR = 3.50, 95% CI = 2.11–4.90, p < 0.00001). However, the change in peak heart rate during and after painful procedures was not statistically significant (RR = −12.14; 95% CI = −29.70−5.41 p = 0.18; RR = −10.41; 95% CI = −22.72−1.90 p = 0.10). Conclusion In conclusion, this systematic review demonstrated that mus...