The long-term outcomes and prognostic factors about locally advanced right colon cancer: a retrospective cohort study

作者：Changzheng Li, Zhenyu Li, Jiachen Zhang, Xijie Zhang, Matthew Wei, Nan Zun Teo, Pengfei Ma, Junli Zhang, Sen Li, Zhi Li, Yuzhou Zhao · 发表于：Journal of Gastrointestinal Oncology · 年份：2024 · DOI：10.21037/jgo-23-928 · 被引用次数：3 · 研究领域：Colorectal Cancer Surgical Treatments、Gastrointestinal Tumor Research and Treatment、Colorectal and Anal Carcinomas

Background: resection for LARCC. We conducted this study to analyze the clinical features and surgical outcomes of LARCC. Methods: A retrospective study was performed using a database of all patients who underwent RHCPD due to the tumour directly invading the duodenum and/or pancreas in a 19-year period [2003-2022]. We included patients whose primary tumor site was the right hemicolon and who had undergone a negative tumor resection margin (R0) resection. In addition, the adhesions between the colon and other organs in these patients were malignant adhesions. The primary outcome was the overall survival after surgery. The secondary endpoints of the study included 30-day postoperative mortality, postoperative complications, prognostic factors, and tumour genetics. All patients were followed up with postoperative imaging at an interval of 3 months for the first 3 years and at an interval of 6 months for the next 2 years, and annual follow-up thereafter. Survival was estimated using Kaplan-Meier analysis. Variables with P values <0.05 in univariate analysis were entered into multivariate Cox proportional risk regression to identify independent predictors of survival. Results: resection for LARCC. The median age of the patients was 61 years (range, 38-80 years). R0 resection was achieved in all cases. The overall complication rate was 27.7% (n=13). Two patients died within 30 days of surgery. The overall survival was 80.9%, 63.5%, and 51.7% at 1, 3, and 5 years, respectively. Uni...