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Complete reference genomes of two ceftriaxone-resistant Neisseria gonorrhoeae strains identified in routine surveillance in Bangkok, Thailand, using Nanopore Q20+ chemistry, VolTRAX V2b, and Illumina sequencing

作者:Pongsathorn Sangprasert, Daniel Golparian, Porntip Paopang, Natnaree Girdthep, Ratana Lawung, Deyer Gopinath, Panithee Thammawijaya, Rossaphorn Kittiyaowanarn, Magnus Unemo · 发表于:Microbiology Resource Announcements · 年份:2024 · DOI:10.1128/mra.01231-23 · 被引用次数:4 · 研究领域:Reproductive tract infections research、Microbial infections and disease research、Bacterial Infections and Vaccines

ABSTRACT Ceftriaxone-resistant Neisseria gonorrhoeae strains, mostly associated with Asia, threaten gonorrhea treatment. We report the reference genomes of two ceftriaxone-resistant isolates found in routine surveillance in Bangkok, Thailand. The genomes belonged to the more antimicrobial-susceptible genomic lineage B, illustrating that both ceftriaxone-resistant strains and the mosaic penA -60.001 ceftriaxone-resistance determinant are spreading.