Koilodenoids A–G, immunosuppressive spiro dimers of diterpenoids from Koilodepas hainanense : structural elucidation and biomimetic transformation

作者：Yu Ren, Cheng‐Yu Zheng, Jiaying Yao, Shijun He, Yao‐Yue Fan, Jian‐Min Yue · 发表于：Organic Chemistry Frontiers · 年份：2024 · DOI：10.1039/d3qo01967e · 被引用次数：6 · 研究领域：Bioactive Natural Diterpenoids Research、Natural product bioactivities and synthesis、Biological Activity of Diterpenoids and Biflavonoids

Seven new and immunosuppressive dimeric diterpenoids were elucidated. Compound 1 possesses a new carbon skeleton. The biomimetic transformation of 2 into 1 was achieved under mild, as well as peroxide- and metal-free conditions.