Organ donation after medical assistance in dying: a descriptive study from 2018 to 2022 in Quebec

作者：Matthew J. Weiss, Mathilde Dupras-Langlais, Marie-Josée Lavigne, Sylvain Lavigne, Annie-Carole Martel, Prosanto Chaudhury · 发表于：Canadian Medical Association Journal · 年份：2024 · DOI：10.1503/cmaj.230883 · 被引用次数：12 · 研究领域：Organ Donation and Transplantation、Organ Transplantation Techniques and Outcomes、Transplantation: Methods and Outcomes

Background: Since the implementation of medical assistance in dying (MAiD), deceased organ donation after MAiD has been possible in Quebec. We sought to describe organ donations after MAiD in the first 5 years after this practice was implemented in Quebec. Methods: We reviewed all cases referred for donation after MAiD from January 2018 to December 2022. We presented all data descriptively with no comparison statistics. Results: Transplant Québec received 245 referrals for donation after MAiD, of which 82 were retained (33.5%). Of the 163 nonretained referrals, 152 (93.2%) had a recorded reason, including 91 (55.8%) for medical unsuitability on initial screen (e.g., organ dysfunction, medical history), 34 (20.8%) for patient refusal and 21 (12.9%) instances where patients withdrew from the MAiD process entirely. Six patients died before MAiD. Eighteen of the 82 retained cases were cancelled later in the process, almost all ( n = 17, 94.4%) because of medical contraindication discovered during detailed donor evaluation. Sixty-four patients became actual donors after MAiD, increasing from 8 in 2018 to 24 in 2022. The total conversion rate from referral to an actual donor was 26.1% (64/245). A total of 182 organs (116 kidneys, 20 livers and 46 lungs) were transplanted after MAiD. During the study period, MAiD donors represented 8.0% (64/803) of total deceased donors, increasing from 4.9% (8/164) in 2018 to 14.0% (24/171) in 2022. Interpretation: These data describe a sub...