Isolated massive pleural effusion as a manifestation of chronic graft versus host disease successfully treated with corticosteroid

作者：Yasutaka Masuda, Sho Yamazaki, Akira Honda, Yosuke Masamoto, Mineo Kurokawa · 发表于：Annals of Hematology · 年份：2024 · DOI：10.1007/s00277-024-05643-w · 被引用次数：4 · 研究领域：Pleural and Pulmonary Diseases、Hematopoietic Stem Cell Transplantation、Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Isolated pleural effusion is a rare manifestation of chronic graft versus host disease (cGVHD) after hematopoietic stem cell transplantation (HSCT). We herein report a 58-year-old woman presenting with massive pleural effusion approximately 1 year after allogeneic HSCT, who was successfully treated with corticosteroid. She had discontinued tacrolimus approximately 1 month before she presented with pleural effusion, which was attributed to cGVHD after a thorough exclusion process. This case illustrates a unique manifestation of atypical cGVHD and highlights the need for prompt therapy initiation.