The apical 70-pS K + channel in the thick ascending limb of Henle’s loop is a large-conductance Na + -and Cl – -activated, K Na 1.1-like, channel

作者：Elise de Combiens, Nadia Frachon, Lydie Cheval, Stéphane Lourdel, Marc Paulais · 发表于：American Journal of Physiology-Renal Physiology · 年份：2024 · DOI：10.1152/ajprenal.00311.2023 · 被引用次数：2 · 研究领域：Ion channel regulation and function、Neuroscience and Neuropharmacology Research、Cardiac electrophysiology and arrhythmias

This study highlights new regulatory and conductive properties of the as yet poorly molecularly defined 70-pS K + channel in the apical membrane of the thick ascending limb of Henle’s loop cells of the mouse kidney that functionally identify it as a large-conductance, Na + - and Cl – -activated K Na 1.1-like channel.