Piezoelectric dressings for advanced wound healing

作者：Jinjun Dai, Jin Shao, Yi Zhang, Ruiyue Hang, Ruiyue Hang, Xiaohong Yao, Long Bai, Ruiqiang Hang, Ruiqiang Hang · 发表于：Journal of Materials Chemistry B · 年份：2024 · DOI：10.1039/d3tb02492j · 被引用次数：43 · 研究领域：Advanced Sensor and Energy Harvesting Materials、Electrospun Nanofibers in Biomedical Applications、Silk-based biomaterials and applications

The treatment of chronic refractory wounds poses significant challenges and threats to both human society and the economy. Existing research studies demonstrate that electrical stimulation fosters cell proliferation and migration and promotes the production of cytokines that expedites the wound healing process. Presently, clinical settings utilize electrical stimulation devices for wound treatment, but these devices often present issues such as limited portability and the necessity for frequent recharging. A cutting-edge wound dressing employing the piezoelectric effect could transform mechanical energy into electrical energy, thereby providing continuous electrical stimulation and accelerating wound healing, effectively addressing these concerns. This review primarily reviews the selection of piezoelectric materials and their application in wound dressing design, offering a succinct overview of these materials and their underlying mechanisms. This study also provides a perspective on the current limitations of piezoelectric wound dressings and the future development of multifunctional dressings harnessing the piezoelectric effect.