Site-selective editing of peptides via backbone modification

作者：Junjie Shi, Tong Sun, Mingyu Yang · 发表于：Organic Chemistry Frontiers · 年份：2024 · DOI：10.1039/d3qo01980b · 被引用次数：15 · 研究领域：Chemical Synthesis and Analysis、Click Chemistry and Applications、Biochemical and Structural Characterization

The site-selective modifications of peptide backbones have a significant impact on peptide conformation, folding ability, and physicochemical and biological properties. This review discusses the site-selective modifications of peptide backbones and classifies them into four categories.