Components and Delivery Formats of Cognitive Behavioral Therapy for Chronic Insomnia in Adults

作者：Yuki Furukawa, Masatsugu Sakata, Ryuichiro Yamamoto, Shun Nakajima, Shino Kikuchi, Mari Inoue, Masami Ito, Hiroku Noma, Hikari Takashina, Satoshi Funada, Edoardo G. Ostinelli, Toshi A. Furukawa, Orestis Efthimiou, Michael L. Perlis · 发表于：JAMA Psychiatry · 年份：2024 · DOI：10.1001/jamapsychiatry.2023.5060 · 被引用次数：150 · 研究领域：Sleep and related disorders、Sleep and Wakefulness Research、Sleep and Work-Related Fatigue

Importance: Chronic insomnia disorder is highly prevalent, disabling, and costly. Cognitive behavioral therapy for insomnia (CBT-I), comprising various educational, cognitive, and behavioral strategies delivered in various formats, is the recommended first-line treatment, but the effect of each component and delivery method remains unclear. Objective: To examine the association of each component and delivery format of CBT-I with outcomes. Data Sources: PubMed, Cochrane Central Register of Controlled Trials, PsycInfo, and International Clinical Trials Registry Platform from database inception to July 21, 2023. Study Selection: Published randomized clinical trials comparing any form of CBT-I against another or a control condition for chronic insomnia disorder in adults aged 18 years and older. Insomnia both with and without comorbidities was included. Concomitant treatments were allowed if equally distributed among arms. Data Extraction and Synthesis: Two independent reviewers identified components, extracted data, and assessed trial quality. Random-effects component network meta-analyses were performed. Main Outcomes and Measures: The primary outcome was treatment efficacy (remission defined as reaching a satisfactory state) posttreatment. Secondary outcomes included all-cause dropout, self-reported sleep continuity, and long-term remission. Results: A total of 241 trials were identified including 31 452 participants (mean [SD] age, 45.4 [16.6] years; 21 048 of 31 452 [67%] wo...