Neonatal mortality risk of vulnerable newborns by fine stratum of gestational age and birthweight for 230 679 live births in nine low‐ and middle‐income countries, 2000–2017

作者：Elizabeth Hazel, Daniel J. Erchick, Joanne Katz, Anne CC Lee, Michael J. Diaz, Lee Wu, Keith P. West, Abu Ahmed Shamim, Parul Christian, Hasmot Ali, Abdullah H Baqui, Samir K. Saha, Salahuddin Ahmed, Arunangshu Dutta Roy, Mariângela Freitas da Silveira, Romina Buffarini, Roger Shapiro, Rebecca Zash, Patrick Kolsteren, Carl Lachat, Lieven Huybregts, Dominique Roberfroid, Zhonghai Zhu, Lingxia Zeng, Seifu Hagos Gebreyesus, Kokeb Tesfamariam, Seth Adu‐Afarwuah, Kathryn G. Dewey, Stephaney Gyaase, Kwaku Poku‐Asante, Ellen Boamah Kaali, Darby Jack, Thulasiraj Ravilla, James M. Tielsch, Sunita Taneja, Ranadip Chowdhury, Per Ashorn, Kenneth Maleta, Ulla Ashorn, Charles Mangani, Luke C. Mullany, Subarna K. Khatry, Vundli Ramokolo, Wanga Zembe‐Mkabile, Wafaie Fawzi, Dongqing Wang, Christentze Schmiegelow, Daniel T. R. Minja, Omari Abdul Msemo, John Lusingu, Emily R. Smith, Honorati Masanja, Aroonsri Mongkolchati, Paniya Keentupthai, Abel Kakuru, Richard Kajubi, Katherine Semrau, Davidson H. Hamer, Albert Manasyan, Jake M. Pry, Bernard Chasekwa, Jean H. Humphrey, Robert E. Black · 发表于：BJOG An International Journal of Obstetrics & Gynaecology · 年份：2024 · DOI：10.1111/1471-0528.17743 · 被引用次数：11 · 研究领域：Global Maternal and Child Health、Maternal and Neonatal Healthcare、Pregnancy and preeclampsia studies

Abstract Objective To describe the mortality risks by fine strata of gestational age and birthweight among 230 679 live births in nine low‐ and middle‐income countries (LMICs) from 2000 to 2017. Design Descriptive multi‐country secondary data analysis. Setting Nine LMICs in sub‐Saharan Africa, Southern and Eastern Asia, and Latin America. Population Liveborn infants from 15 population‐based cohorts. Methods Subnational, population‐based studies with high‐quality birth outcome data were invited to join the Vulnerable Newborn Measurement Collaboration. All studies included birthweight, gestational age measured by ultrasound or last menstrual period, infant sex and neonatal survival. We defined adequate birthweight as 2500–3999 g (reference category), macrosomia as ≥4000 g, moderate low as 1500–2499 g and very low birthweight as <1500 g. We analysed fine strata classifications of preterm, term and post‐term: ≥42 +0 , 39 +0 –41 +6 (reference category), 37 +0 –38 +6 , 34 +0 –36 +6 ,34 +0 –36 +6 ,32 +0 –33 +6 , 30 +0 –31 +6 , 28 +0 –29 +6 and less than 28 weeks. Main outcome measures Median and interquartile ranges by study for neonatal mortality rates (NMR) and relative risks (RR). We also performed meta‐analysis for the relative mortality risks with 95% confidence intervals (CIs) by the fine categories, stratified by regional study setting (sub‐Saharan Africa and Southern Asia) and study‐level NMR (≤25 versus >25 neonatal deaths per 1000 live births). Results We found a dos...