Photocatalytic aerobic oxidation of C(sp3)-H bonds

作者：Lei Zhang, Run‐Han Li, Xiaoxin Li, Shengyao Wang, Jiang Liu, Xiao-Xuan Hong, Long‐Zhang Dong, Shun‐Li Li, Ya‐Qian Lan · 发表于：Nature Communications · 年份：2024 · DOI：10.1038/s41467-024-44833-y · 被引用次数：90 · 研究领域：Oxidative Organic Chemistry Reactions、Radical Photochemical Reactions、Catalytic C–H Functionalization Methods

Abstract In modern industries, the aerobic oxidation of C(sp 3 )-H bonds to achieve the value-added conversion of hydrocarbons requires high temperatures and pressures, which significantly increases energy consumption and capital investment. The development of a light-driven strategy, even under natural sunlight and ambient air, is therefore of great significance. Here we develop a series of hetero-motif molecular junction photocatalysts containing two bifunctional motifs. With these materials, the reduction of O 2 and oxidation of C(sp 3 )-H bonds can be effectively accomplished, thus realizing efficient aerobic oxidation of C(sp 3 )-H bonds in e.g., toluene and ethylbenzene. Especially for ethylbenzene oxidation reactions, excellent catalytic capacity (861 mmol g cat −1 ) is observed. In addition to the direct oxidation of C(sp 3 )-H bonds, CeBTTD-A can also be applied to other types of aerobic oxidation reactions highlighting their potential for industrial applications.