Pneumothorax and pulmonary hemorrhage after C-arm cone-beam computed tomography-guided percutaneous transthoracic lung biopsy: incidence, clinical significance, and correlation

作者：Yanjie Yang, Jingqin Ma, Zhijie Peng, Xin Zhou, Nan Du, Wen Zhang, Zhiping Yan · 发表于：BMC Pulmonary Medicine · 年份：2024 · DOI：10.1186/s12890-023-02822-9 · 被引用次数：6 · 研究领域：Lung Cancer Diagnosis and Treatment、Pleural and Pulmonary Diseases、Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Abstract Objective This study aimed to assess the incidence and clinical significance of pneumothorax (PTX) and pulmonary hemorrhage (PH) after percutaneous transthoracic lung biopsy (PTLB) guided by C-arm cone-beam computed tomography (CBCT). Furthermore, this study aimed to examine the relationships between PTX and PH with demographics, clinical characteristics, imaging, and PTLB parameters. Methods A retrospective analysis was conducted on 192 patients who underwent PTLB at our hospital between January 2019 and October 2022. Incidences of PTX and PH were recorded. PTX was considered clinically significant if treated with chest tube insertion (CTI), and PH if treated with bronchoscopes or endovascular treatments. The various factors on PTX and PH were analyzed using the Chi-squared test and Student t-test. Logistic regression analyses were then used to determine these factors on the correlation to develop PTX and PH. Results PTX occurred in 67/192 cases (34.9%); CTI was required in 5/67 (7.5%). PH occurred in 63/192 cases (32.8%) and none of these cases required bronchoscopes or endovascular treatments. Lesion diameter (OR PTX = 0.822; OR PH = 0.785), presence of pulmonary emphysema (OR PH = 2.148), the number of samples (OR PH = 1.834), the use of gelfoam (OR PTX = 0.474; OR PH = 0.341) and ablation (OR PTX = 2.351; OR PH = 3.443) showed statistically significant correlation to PTX and PH. Conclusions CBCT-guided PTLB is a safe and effective method for performing lung biop...