Mpox knowledge and vaccination hesitancy among healthcare workers in Beijing, China: A cross-sectional survey

作者：Yuan Yang, Weijie Zhang, Baihui Han, Han Meng, Jiaqi Wang, Ke Wu, Leiwen Fu, Bingyi Wang, Xiaohong Jiang, Qian Li, Zhiyuan Xu, Ye Zhang, Xiao Qi, Huachun Zou · 发表于：Vaccine X · 年份：2024 · DOI：10.1016/j.jvacx.2024.100434 · 被引用次数：14 · 研究领域：Poxvirus research and outbreaks、Vaccine Coverage and Hesitancy、Immune responses and vaccinations

Background: Mpox, one of the most serious threats to global health, is now being seen in small but rising numbers in Beijing, China. Our study aimed to investigate healthcare workers' (HCWs) knowledge of Mpox and to explore reasons associated with their hesitancy to vaccinate against Mpox in Beijing, China. Methods: A cross-sectional study was conducted among HCWs in Beijing from July 24 to August 2, 2023, through an online questionnaire. Participants answered questions about sociodemographic characteristics, Mpox information sources, Mpox knowledge, perception of vaccines, and attitudes toward Mpox vaccination. We used Chi-squared test to compare difference in Mpox vaccination hesitancy between different groups. Multivariable logistic regression models were applied to analyze correlates of vaccination hesitancy among HCWs. Results: A total of 2331 HCWs completed the questionnaire, with an effective response rate of 92.45 % (2155/2331). Most of the HCWs in this study worked at tertiary hospitals (89.65 %), with a mean age of 36.69 ± 9.08 years. Among the 2155 participants, 52.99 % had over ten years of working experience, and 16.66 % were from high-risk departments relevant to Mpox treatment. Approximately 84.41 % knew about Mpox before this study, 80.79 % exhibited a high level of knowledge about Mpox, whereas 42.37 % were hesitant to be vaccinated against Mpox. Moreover, the hesitancy rate of HCWs in high-risk departments (47.91 %) was higher than in lower-risk departments ...