Microbial Mechanistic Insight into the Role of Yeast−Derived Postbiotics in Improving Sow Reproductive Performance in Late Gestation and Lactation Sows

作者：Junlei Chang, Xinlin Jia, Yalei Liu, Xuemei Jiang, Lianqiang Che, Yan Lin, Yong Zhuo, Bin Feng, Zhengfeng Fang, Jian Li, Lun Hua, Jianping Wang, Zhihua Ren, De Wu, Shengyu Xu · 发表于：Animals · 年份：2024 · DOI：10.3390/ani14010162 · 被引用次数：14 · 研究领域：Animal Behavior and Welfare Studies、Gut microbiota and health、Human-Animal Interaction Studies

The purpose of this study is to investigate the effects of supplementing Yeast−derived postbiotics (Y−dP) to the diet of sows during late pregnancy and lactation on fecal microbiota and short−chain fatty acids (SCFA) in sows and their offspring weaned piglets, as well as the relationship between gut microbiota and SCFA, serum cytokines, and sow reproductive performance. A total of 150 sows were divided into three groups: control diet (CON), CON + Y−dP 1.25 g/kg, and CON + Y−dP 2 g/kg. The results showed that supplementing 0.125% Y−dP to the diet of sows can increase the content of isobutyric acid (IBA) in the feces of pregnant sows and reduce the content of butyric acid (BA) in the feces of weaned piglets (p < 0.05). The fecal microbiota of pregnant sows β diversity reduced and piglet fecal microbiota β diversity increased (p < 0.05). Y−dP significantly increased the abundance of Actinobacteria and Limosilactobacilli in the feces of pregnant sows (p < 0.05), as well as the abundance of Verrucomicrobiota, Bacteroidota, and Fusobacteriota in the feces of piglets (p < 0.05). The abundance of Bacteroidota in the feces of pregnant sows is positively correlated with propionic acid (PA) (r > 0.5, p < 0.05). The abundance of Prevotellaceae_NK3B31_group was positively correlated with Acetic acid (AA), PA, Valerate acid (VA), and total volatile fatty acid (TVFA) in the feces of pregnant sows (r > 0.5, p < 0.05), and Bacteroidota and Prevotellaceae_NK3B31_group w...