Dual-network DNA–silk fibroin hydrogels with controllable surface rigidity for regulating chondrogenic differentiation

作者：Ziyang Zhou, Peiran Song, Yan Wu, Miaomiao Wang, Congyi Shen, Zhixin Ma, Xiaoxiang Ren, Xiuhui Wang, Xiao Chen, Yan Hu, Zuhao Li, Qin Zhang, Mengmeng Li, Zhen Geng, Jiacan Su · 发表于：Materials Horizons · 年份：2024 · DOI：10.1039/d3mh01581e · 被引用次数：90 · 研究领域：Silk-based biomaterials and applications、Osteoarthritis Treatment and Mechanisms、Hydrogels: synthesis, properties, applications

studies revealed that dual-network DNA-SF hydrogels with moderate surface rigidity significantly accelerated cartilage regeneration. In summary, the dual-network DNA-SF hydrogels represent a promising and novel therapeutic strategy for cartilage regeneration.