Malachite green: a long-buried water-soluble AIEgen with near-infrared fluorescence for living cell nucleus staining

作者：Yuan Luo, Lihua Zhou, Lili Du, Yangzi Xie, Xiang-Yang Lou, Lintao Cai, Ben Zhong Tang, Ping Gong, Pengfei Zhang · 发表于：Chemical Communications · 年份：2024 · DOI：10.1039/d3cc05535c · 被引用次数：14 · 研究领域：Luminescence and Fluorescent Materials、Nanoplatforms for cancer theranostics、Photoreceptor and optogenetics research

Fluorescent imaging probes are crucial for exploring nucleus-related cellular events in live cells. Ideal probes should be photostable, small-sized, highly contrasted, and low in background. Here, we discovered that malachite green is a water-soluble near-infrared luminogen with aggregation-induced emission properties. Importantly, it can be used for living cell nucleus staining in a wash-free manner.