Immunocompetent mouse models revealed that S100A4 + monocytes/macrophages facilitate long-term Zika virus infection in the testes

作者：Wei Yang, Chen Zhang, Libo Liu, Zhan-Zhan Bian, Jia-Tong Chang, Dongying Fan, Na Gao, Peigang Wang, Jing An · 发表于：Emerging Microbes & Infections · 年份：2024 · DOI：10.1080/22221751.2023.2300466 · 被引用次数：15 · 研究领域：Mosquito-borne diseases and control、Viral Infections and Vectors、COVID-19 Impact on Reproduction

monocytes/macrophages had a great impact on the microenvironment of ZIKV-infected testes, thus promoting ZIKV-induced testicular lesions. In conclusion, this study proposed a novel mechanism of long-term ZIKV infection in the male reproductive system.