Pneumothorax after percutaneous CT-guided lung nodule biopsy: a prospective, multicenter study

作者：Chuang He, Ling Zhao, Hualong Yu, Wei Zhao, Dong Li, Guodong Li, Hao Wang, Bin Huo, Qiming Huang, Bai-wu Liang, Rong Ding, Zhe Wang, Chen Liu, Liang-Yu Deng, Jun-Ru Xiong, Xuequan Huang · 发表于：Quantitative Imaging in Medicine and Surgery · 年份：2023 · DOI：10.21037/qims-23-891 · 被引用次数：20 · 研究领域：Lung Cancer Diagnosis and Treatment、Pleural and Pulmonary Diseases、Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Background: Pneumothorax is a common complication induced by computed tomography (CT)-guided percutaneous needle biopsy, with a frequency of 17–40.4%. It remains debatable how to predict and prevent the occurrence of post-biopsy pneumothorax. In a real-world setting, we investigated the characteristics associated with pneumothorax in primary lung nodule biopsy. Methods: This clinical registry cohort study recorded patients with newly diagnosed pulmonary nodules from 10 medical centers from April 2021 to April 2022, and the data were input into the electronic data capture (EDC) system. The eligibility criteria for participants included being within the age range of 18 to 80 years and expressing a willingness to undergo percutaneous puncture biopsy, among other requirements. Conversely, the exclusion criteria included an inability to cooperate throughout the biopsy process and the emergence of new health issues during the study duration resulting in attendance delays, among other factors. This study collected data from 924 patients, out of which 593 were included after exclusion. The essential characteristics, imaging features of pulmonary nodules, and technical factors associated with percutaneous biopsy were recorded. T-tests or one-way analysis of variance (ANOVA) were performed for continuous variables and Pearson’s χ2 test, likelihood ratio, or Fisher’s exact test were applied for categorical variables for comparison as appropriate, followed by multivariate logistic regres...