Impact of the COVID-19 pandemic on the coverage and timeliness of routine childhood vaccinations in the Gambia, 2015–2021

作者：Oghenebrume Wariri, C. Edson Utazi, Uduak Okomo, Alieu Sowe, Malick Sogur, Sidat Fofanna, Esu Ezeani, Lamin Saidy, Golam Sarwar, Bai-Lamin Dondeh, Kris A. Murray, Chris Grundy, Beate Kampmann · 发表于：BMJ Global Health · 年份：2023 · DOI：10.1136/bmjgh-2023-014225 · 被引用次数：10 · 研究领域：Vaccine Coverage and Hesitancy、Immune responses and vaccinations、SARS-CoV-2 and COVID-19 Research

INTRODUCTION: The COVID-19 pandemic caused widespread morbidity and mortality and resulted in the biggest setback in routine vaccinations in three decades. Data on the impact of the pandemic on immunisation in Africa are limited, in part, due to low-quality routine or administrative data. This study examined coverage and timeliness of routine childhood immunisation during the pandemic in The Gambia, a country with an immunisation system considered robust. METHODS: We obtained prospective birth cohort data of 57 286 children in over 300 communities in two health and demographic surveillance system sites, including data from the pre-pandemic period (January 2015-February 2020) and the three waves of the pandemic period (March 2020-December 2021). We determined monthly coverage and timeliness (early and delayed) of the birth dose of hepatitis B vaccine (HepB0) and the first dose of pentavalent vaccine (Penta1) during the different waves of the pandemic relative to the pre-pandemic period. We implemented a binomial interrupted time-series regression model. RESULT: We observed no significant change in the coverage of HepB0 and Penta1 vaccinations from the pre-pandemic period up until the periods before the peaks of the first and second waves of the pandemic in 2020. However, there was an increase in HepB0 coverage before as well as after the peak of the third wave in 2021 compared with the pre-pandemic period (pre-third wave peak OR = 1.83, 95% CI 1.06 to 3.14; post-third wave per...