Exceptional Response to MEK Inhibition in a Patient With RAF1-Mutant Myxofibrosarcoma: Case Report and Mechanistic Overview

作者：Eylül Özgü, Esranur Aydın, Ashkan Adibi, Ünal Metin Tokat, Onur Tutar, Jiancheng Hu, İrem Demiray, Razelle Kurzrock, Mutlu Demiray · 发表于：JCO Precision Oncology · 年份：2023 · DOI：10.1200/po.23.00299 · 被引用次数：8 · 研究领域：Sarcoma Diagnosis and Treatment、Melanoma and MAPK Pathways、Peptidase Inhibition and Analysis

Complete response to Trametinib in a heavily-pretreated sarcoma: RAF1 as a predictor of MEKi Response