Association between ambient particulate matters and anhedonia among patients with depression

作者：Tianqin Xie, Yu Zhang, Hui Kong, Lianzi Guan, Lei Zhang, Jiakuai Yu, Peng Zhu, Shuangshuang Ma, Daomin Zhu · 发表于：Environmental Science and Pollution Research · 年份：2023 · DOI：10.1007/s11356-023-31474-9 · 被引用次数：1 · 研究领域：Air Quality and Health Impacts、Health disparities and outcomes、Psychological and Temporal Perspectives Research

Abstract Recent studies have linked ambient air pollution to depression. Anhedonia is a core symptom of depression which severely impacts on prognosis. The present study aims to investigate the association of PM2.5 and PM10 exposure with anhedonia in depressed patients. A total of 538 patients with depression who were hospitalized at the Fourth People’s Hospital of Hefei between June 2017 and December 2021 were included. We estimated ambient particulate matters exposure, including PM2.5 and PM10, using a satellite-based spatiotemporal model at a resolution of 1 km 2 . The revised Physical Anhedonia Scale (RPAS) and the revised Social Anhedonia Scale (RSAS) were evaluated. The association of ambient particulate matters and anhedonia was examined using multiple linear regression models, adjusted for potential confounders. We observed that exposure to PM2.5 were significantly associated with increased RSAS score and RPAS score, with the major effect in the 12-month exposure window ( β = 1.238; 95%CI, 0.353, 2.123) and 18-month exposure window ( β = 1.888; 95%CI, 0.699, 3.078), respectively. Meanwhile, PM10 levels were also significantly associated with increased RSAS score and RPAS score, with the major effect in the 18-month exposure window ( β = 1.220; 95%CI, 0.439, 2) and 3-month exposure window ( β = 1.602; 95%CI, 0.062, 3.143), respectively. Subgroup analysis showed that both PM2.5 and PM10 were significantly associated with anhedonia in females, patients < 40 years old,...