Sulfination of Unactivated Allylic Alcohols via Sulfinate–Sulfone Rearrangement

作者：Yan Wang, Guangming Wu, Kaiyu Yan, Jiaheng Qin, Rui Liu, Nannan Rong, Yongming Tang, Teck‐Peng Loh, Peizhong Xie · 发表于：Organic Letters · 年份：2023 · DOI：10.1021/acs.orglett.3c03709 · 被引用次数：7 · 研究领域：Sulfur-Based Synthesis Techniques、Chemical Synthesis and Reactions、Catalytic C–H Functionalization Methods

A dehydrative cross-coupling of unactivated allylic alcohols with sulfinic acids was achieved under catalyst-free conditions. This reaction proceeded via allyl sulfination and concomitant allyl sulfinate-sulfone rearrangement. Various allylic sulfones could be obtained in good to excellent yields with water as the only byproduct. This study expands the synthetic toolbox for constructing allylic sulfone molecules.