Global research trends and prospects related to tumor microenvironment within Triple Negative Breast Cancer: a bibliometric analysis

作者：Peiting Li, Jun Li, Xiaofei Tong, Zhenyang Xiao, Wuliang Diao, Chi Zhong, Jianda Zhou, Wei Wu · 发表于：Frontiers in Immunology · 年份：2023 · DOI：10.3389/fimmu.2023.1261290 · 被引用次数：10 · 研究领域：Cancer Immunotherapy and Biomarkers、Immune cells in cancer、Cancer Cells and Metastasis

Background and aims The tumor microenvironment (TME) has pivotal parts within multiple tumor models of onset/progression, such as triple-negative breast cancer (TNBC). This bibliometric analysis was developed to explore trends and research niches revolving around TME in TNBC. Methods Web of Science Core Collection was queried for identifying studies linked with TME in TNBC, after which the VOSviewer, CiteSpace, and R software programs were used to conduct bibliometric analyses and to generate corresponding visualizations. Results In total, this study included 1,604 studies published from 2005-2023. The USA and China exhibited the highest numbers of citations, and the research institutions with the greatest output in this field included Harvard University, the University of Texas System, and Fudan University. Ying Wang from Sun Yat-Sen University was the most published and most cited author in this space. The highest number of articles were published in Cancer , while the greatest co-citation number was evident in Breast Cancer Research . Important keywords related to this research topic included metastasis, tumor-infiltrating lymphocytes, immunotherapy, chemotherapy, and nanoparticles. In particular, pembrolizumab, immunotherapy, nanoparticles, combination treatment, and biomarkers were topics of marked interest in recent reports. Conclusion The TME in TNBC is an area of rapidly growing and evolving research interest, with extensive global collaboration helping to drive this ...